TL: DR - has significantly improved treatment resistant MDD, improved menstrual problems, improved libido and connection. May as well be magic.. I have lived with treatment resistant major depressive disorder and anxiety for more than 20 years. Any medication we tried only made things worse. I had resigned myself to living like this. I went to see my physician because my symptoms became acutely worse and I was no longer safe. She hesitantly prescribed yet another medication, but mentioned "off the record" that saffron was showing great efficacy, better than SSRIs, in double blind studies. I told her I'd try that instead as I had no hope for the prescription. Within a few days, it was magic. I had my full range of emotions, but they were situational appropriate. My fatigue was decreased, I was sleeping well, the brain fog lifted, and I felt better than I had in more years than i can remember. It also has brought back the libido I had in my early 20s which i thought was a lost cause. Now, two months in, I am still feeling good with some mild variability and an occasional bad day, which is still a world of improvement. As a side note, I have also struggled with hemorrhage level bleeding and debilitating cramps during menstruation, and my last cycle was normal-person normal. I only finally connected these a couple days ago, when I realized that ashwaganda can improve menstruation and fertility, but fingers crossed that that continues as well. Will this work for everyone? No, nothng does. Is it worth a try? Absolutely.
